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Publications from Brown

31. Bilotti, K., Kennedy, E.E., Li, C. and Delaney, S. Human OGG1 activity in nucleosomes is facilitated by transient
unwrapping of DNA and is influenced by the local histone environment. DNA Repair. 2017, 59, 1. [link]

30. Olmon, E.D. and Delaney, S. Differential ability of five DNA glycosylases to recognize and repair damage on
nucleosomal DNA. ACS Chem. Biol. 2017, 12, 692. [link] **Featured on Cover of March 17, 2017 issue. [link]

29. Huang, J. and Delaney, S. Unique length-dependent biophysical properties of repetitive DNA. J. Phys. Chem. B.
2016
, 120, 4195. [link]

28. Huang, J., Yennie, C. J., and Delaney, S. Klenow fragment discriminates against the incorporation of the
hyperoxidized dGTP lesion spiroiminodihydantoin into DNA. Chem. Res. Toxicol. 2015, 28, 2325. [link]

27. Tarantino, M.E., Bilotti, K., Huang, J., and Delaney, S. Rate-determining step of flap endonuclease 1 (FEN1)
reflects a kinetic bias against long flaps and trinucleotide repeat sequences. J. Biol. Chem. 2015, 290, 21254. [link]

26. Schermerhorn, K. M. and Delaney, S. A chemical and kinetic perspective on base excision repair of DNA.
Acc. Chem. Res. 2014, 47, 1238-1246. [link]

25. Volle C. B. and Delaney S. AGG/CCT interruptions affect nucleosome formation and positioning of
healthy-length CGG/CCG triplet repeats. BMC Biochemistry. 2013, 14, 1-12. [link]

24. Schermerhorn, K. M. and Delaney, S. Transient-state kinetics of apurinic/apyrimidinic (AP) endonuclease 1
acting on an authentic AP site and commonly-used substrate analogs: The effect of diverse metal ions and base
mismatches. Biochemistry. 2013, 52, 7669-7677. [link]

23. Volle, C. B. and Delaney, S. CAG/CTG repeats alter affinity for the histone core and positioning of DNA
in the nucleosome. Biochemistry. 2012, 51, 9814-9825. [link]

22. Yennie, C. J. and Delaney, S. Thermodynamic consequences of the hyperoxidized guanine lesion
guanidinohydantoin in duplex DNA. Chem. Res. Toxicol. 2012, 25, 1732-1739. [link]

21. Delaney, S., Jarem, D. A., Volle, C. B., and Yennie, C. J. Chemical and biological consequences of
oxidatively damaged guanine in DNA. Free Rad. Res. 2012, 46, 420-441. [link]

20. Volle, C. B., Jarem, D. A., and Delaney, S.Trinucleotide repeat DNA alters structure to minimize the
thermodynamic impact of 8-oxo-7,8-dihydroguanine. Biochemistry 2012, 51, 52-62. [link]

19. Jarem, D. A. and Delaney, S. Premutation huntingtin allele adopts a non-B conformation and contains
a hot spot for DNA damage. Biochem. Biophys. Res. Comm. 2011, 416, 146-152. [link]

18. Avila Figueroa, A.; Cattie, D. J.; Delaney, S. A small unstructured nucleic acid disrupts a trinucleotide repeat
hairpin. Biochem. Biophys. Res. Comm. 2011, 413, 532-536. [link]

17. Jarem, D. A.; Wilson, N. R.; Schermerhorn, K. M.; Delaney, S. Incidence and persistence of
8-oxo-7,8-dihydroguanine within a hairpin intermediate exacerbates a toxic oxidation cycle associated with
trinucleotide repeat expansion. DNA Repair 2011, 10, 887-896. [link]

16. Cooper, D. C., Yennie, C. J., Morin, J. B., Delaney, S. , and Suggs, J. W. Development of a DNA-damaging
ferrocene amino acid. J. Organomet. Chem. 2011, 696, 3058-3061. [link]

15. Avila Figueroa, A.; Cattie, D. J.; Delaney, S. Structure of even/odd trinucleotide repeat sequences modulates
persistence of non-B conformations and conversion to duplex. Biochemistry 2011, 50, 4441-4450. [link]

14. Jarem, D. A.; Huckaby, L. V.; Delaney, S. AGG interruptions in (CGG)n DNA repeat tracts modulate the
structure and thermodynamics of non-B conformations in vitro. Biochemistry 2010, 49, 6826-6837. [link]

13. Avila Figueroa, A.; Delaney, S. Mechanistic studies of hairpin to duplex conversion for trinucleotide repeat
sequences. J. Biol. Chem. 2010, 285, 14648-14657. [link]

12. Jarem, D. A.; Wilson, N. R.; Delaney, S. Structure-dependent DNA damage and repair in a trinucleotide
repeat sequence. Biochemistry 2009, 48, 6655-6663. [link]

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Prior publications

11. Delaney, S.; Delaney, J. C.; Essigmann, J. M. Chemical-Biological Fingerprinting: Probing the properties
of DNA lesions formed by peroxynitrite. Chem. Res. Toxicol. 2007, 20, 1718-1729. [link]

10. Neeley, W. L.; Delaney, S.; Alekseyev, Y. O.; Jarosz, D. F.; Delaney, J. C.; Walker, G. C.; Essigmann, J. M.
DNA polymerase v allows bypass of toxic guanine oxidation products in vivo. J. Biol. Chem. 2007, 282,
12741-12748. [link]

9. Delaney, S.; Neeley, W. L.; Delaney, J. C.; Essigmann, J. M. The substrate specificity of MutY for
hyperoxidized guanine lesions in vivo. Biochemistry 2007, 46, 1448-1455. [link]

8. Delaney, S.; Yoo, J.; Stemp, E. D.; Barton, J. K. Charge equilibration between two distinct sites in double
helical DNA. Proc. Natl. Acad. Sci. U. S. A. 2004, 101, 10511-10516. [link]

7. Yoo, J.; Delaney, S.; Stemp, E. D.; Barton, J. K. Rapid radical formation by DNA charge transport through
sequences lacking intervening guanines. J. Am. Chem. Soc. 2003, 125, 6640-6641. [link]

6. Delaney, S.; Barton, J. K. Long-range DNA charge transport. J. Org. Chem. 2003, 68, 6475-6483. [link]

5. Delaney, S.; Barton, J. K. Charge transport in DNA duplex/quadruplex conjugates. Biochemistry 2003, 42,
14159-14165. [link]

4. Delaney, S.; Pascaly, M.; Bhattacharya, P. K.; Han, K.; Barton, J. K. Oxidative damage by ruthenium complexes
containing the dipyridophenazine ligand or its derivatives:  A focus on intercalation. Inorg. Chem. 2002, 41,
1966-1974. [link]

3. Choi, S.; Delaney, S.; Orbai, L.; Padgett, E. J.; Hakemian, A. S. A platinum(IV) complex oxidizes guanine to
8-oxo-guanine in DNA and RNA. Inorg. Chem. 2001, 40, 5481-5482. [link]

2. Choi, S.; Mahalingaiah, S.; Delaney, S.; Neale, N. R.; Masood, S. Substitution and reduction of platinum(IV)
complexes by a nucleotide, guanosine 5'-monophosphate. Inorg. Chem. 1999, 38, 1800-1805. [link]

1. Choi, S.; Filotto, C.; Bisanzo, M.; Delaney, S.; Lagasee, D.; Whitworth, J. L.; Jusko, A.; Li, C. R.; Wood, N. A.;
Willingham, J.; Schwenker, A.; Spaulding, K. Reduction and anticancer activity of platinum(IV) complexes. Inorg.
Chem.
1998, 37, 2500-2504. [link]